This is a perfect use case for a long ugly password—long and ugly for hackers and long and ugly for remembering (no way)! A perfect way to use 1Password.
The main issue I ran into at Coinbase.com was an apparent incompatibility with Apple Safari web browser: entering the code for 2-factor authentication hangs (the web site never finishes and accepts). I’ve reported this bug to them, but they do not offer any notification or ETA on fixes. Google Chrome works fine however.