My number one recommended configuration of the 2013 Mac Pro is the 6-core with 1TB SSD (flash).
Note that MPG strongly recommends getting the 1TB flash option because there is no upgrade path at this time. 512GB might be OK for some users, but avoid the 256GB option (too small).
At this time MPG considers the D300 GPUs a fine choice for the vast majority of users (video use excepted), so don’t sweat the GPUs, meaning the “faster” GPUs remain unproven as to any merit over the D300 GPUs.
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Stuff you’ll want