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Disable Safari’s 'Open Safe Files by Default'
With the advent of javascript-drive trojan horses like MacDefender (a classic use of a anti-name to confuse and mislead), it’s best not to download anything from any site you don’t trust.
Worse, opening downloaded files automatically is a Very Bad Idea. So make sure the checkbox is off, and if Apple removed this option it would be a good idea.

Ensure that Safari’s
is off (not checked)